Primary Identifier | MGI:6304420 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Mc4r |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
description | https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4169 |
molecularNote | ENU-induced A to T transversion at base pair 66,859,856 (v38) on chromosome 18, or base pair 632 in the GenBank genomic region NC_000084 for the Mc4r gene. The mutation corresponds to residue 632 in the mRNA sequence NM_016977 within exon 1 of 1 total exons. The mutation results in an asparagine to isoleucine substitution at position 62 (N62I) in the MC4R protein. |