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Allele : Card11<M7Btlr> caspase recruitment domain family, member 11; mutation 7, Bruce Beutler

Primary Identifier  MGI:6304449 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Card11
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
description  https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=4190
molecularNote  ENU-induced A to T transversion at base pair 140,913,309 (v38) on chromosome 5, or base pair 87,288 in the GenBank genomic region NC_000071 encoding Card11. The mutation corresponds to residue 430 in the mRNA sequence NM_175362 within exon 3 of 25 total exons. The mutation results in an isoleucine to phenylalanine substitution at position 37 (I37F) in the CARMA1 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Caravaggio,
  • Caravaggio
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele