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Allele : Tnnc1<tm1.1Jrpi> troponin C, cardiac/slow skeletal; targeted mutation 1.1, Jose R Pinto
Primary Identifier  MGI:6304486 Allele Type  Targeted
Attribute String  Not Specified Gene  Tnnc1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A substitution of alanine for valine (A8V) at position 8 was introduced in exon 1 in the N-helix and a loxP-flanked neomycin selection cassette was inserted in intron 1. Cre-mediated recombination removed the neo cassette. This a human hypertrophic cardiomyocyte-associated mutation.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • KI-TnC-A8V<+>,
  • KI-TnC-A8V<+>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories





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