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Allele : Sacs<em2(IMPC)Tcp> sacsin; endonuclease-mediated mutation 2, The Centre for Phenogenomics

Primary Identifier  MGI:6316211 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Sacs
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0556 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of AAGAAATAAGTTGCCCTCAT and ATACCTGATTGGATCAAGAT targeting the 5' side and CCAGTTGGTAGTATCCTTAG and CTTGCTCCCACTCTGAAGTG targeting the 3' side of exons ENSMUSE00000558006, ENSMUSE00000558005, and ENSMUSE00000558003 resulting in a 5734-bp deletion of Chr14 from 61179235 to 61184968 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories