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Allele : Tedc1<em2(IMPC)Tcp> tubulin epsilon and delta complex 1; endonuclease-mediated mutation 2, The Centre for Phenogenomics

Primary Identifier  MGI:6316220 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tedc1
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0759 was generated at The Centre for Phenogenomics by electroporating Cas9 ribnucleoprotein complexes with four guide RNAs having spacer sequences of CACTACTACCCAGGTAAGCG and GCTAACCTGGAGATTTCACC targeting the 5' side and CTGTTGGGGAAATACCCGGC and GATACGTCAGGTAGAACTAG targeting the 3' side of exons ENSMUSE00000438166, ENSMUSE00000374366, and ENSMUSE00000304458 resulting in a 1249-bp deletion of Chr12 from 113157052 to 113158300 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories