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Allele : Recql4<em1Crwy> RecQ protein-like 4; endonuclease-mediated mutation 1, Carl R Walkley
Primary Identifier  MGI:6342633 Allele Type  Endonuclease-mediated
Gene  Recql4 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an AAG to GCA change resulting in a lysine to alanine mutation at amino acid 525 (K525A). This mutation abolishes ATP-dependent helicase activity.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Recql4<K525A>,
  • Recql4<tm4Crw>,
  • Recql4<tm4Crw>,
  • Recql4<K525A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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