Primary Identifier | MGI:6342633 | Allele Type | Endonuclease-mediated |
Gene | Recql4 | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated an AAG to GCA change resulting in a lysine to alanine mutation at amino acid 525 (K525A). This mutation abolishes ATP-dependent helicase activity. |