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Allele : Lrp4<tm1.1Htsh> low density lipoprotein receptor-related protein 4; targeted mutation 1.1, Hiroshi Tanahashi

Primary Identifier	MGI:6342781	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Lrp4
Transmission	Germline	Strain of Origin	B6.Cg-Thy1<a>
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated mutation removes exon 1 and the selection cassette.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Tanahashi H, et al. (2016) Polyhydramnios in Lrp4 knockout mice with bilateral kidney agenesis: Defects in the pathways of amniotic fluid clearance. Sci Rep 6:20241

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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