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Allele : Septin12<em1Haiy> septin 12; endonuclease-mediated mutation 1, Haiyuan Yu

Primary Identifier  MGI:6363494 Allele Type  Endonuclease-mediated
Attribute String  Hypomorph Gene  Septin12
Strain of Origin  (FVB/NJ x B6(Cg)-Tyr<c-2J>/J)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technology and an sgRNA and an ssODN template oligonucleotide, an allele was created with a GC>AG mutation leading to a p.G167E substitution in the encoded peptide (equivalent to p.G169E in the human ortholog).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Sept12<G169E>,
  • Sept12<G169E>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories