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Allele : Agk<em1Qiz> acylglycerol kinase; endonuclease-mediated mutation 1, Qiang Zou

Primary Identifier	MGI:6381662	Allele Type	Endonuclease-mediated
Attribute String	Not Specified	Gene	Agk
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

Using CRISPR/Cas9 technology, glycine codon 126 (GGC) was changed to a glutamic acid codon (GAA) (p.Gly126Glu). This creates a kinase-dead version of the peptide that is unable to phosphorylate its target lipids.

mutations:
Nucleotide substitutions

synonyms:
Agk<G126E>,
Agk<G126E>,
AGK-G126E PM,
AGK-G126E PM

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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