| Primary Identifier | MGI:6342949 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Scn1a |
| Strain of Origin | 129S1/SvImJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 genome editing is used to introduce an A>T point mutation at nucleotide 1837 (converting arginine (R) 613 to a STOP (X) codon) and a silent C>T mutation at position 1833 into exon 12. Mutations in Scn1a are associated with Dravet Syndrome. |
