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Allele : Spaar<em1Ppp> small regulatory polypeptide of amino acid response; endonuclease-mediated mutation 1, Pier Paolo Pandolfi

Primary Identifier	MGI:6343396	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout	Gene	Spaar
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

A deletion of the initiation ATG codon was generated by CRISPR/Cas9 mutagenesis in order to ablate the polypeptide expression while maintaining the expression of the host lncRNA. Immunoblot analysis confirmed the absence of polypeptide expression in skeletal muscle from homozygous mutant mice.

mutations:
Intragenic deletion

synonyms:
Spar<->,
Spar<->

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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