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Allele : Tnni3<em1(dre)Bzsh> troponin I, cardiac 3; endonuclease-mediated mutation 1, Bin Zhou
Primary Identifier  MGI:6386758 Allele Type  Endonuclease-mediated
Attribute String  Recombinase Gene  Tnni3
Strain of Origin  Not Specified Is Recombinase  true
Is Wild Type  false
molecularNote  A cDNA encoding Dre recombinase was iserted into the site encoding the translational start codon of the Krt19 gene, using the CRISPR/Cas9 technology. The woodchuck hepatitis virus post-transcriptional regulatory element (WPRE) were placed after the Dre cDNA sequence to stabilize the Dre-encoding mRNA.
  • mutations:
  • Insertion
  • synonyms:
  • Tnni3-Dre,
  • Tnni3-Dre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

7 Publication categories





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