| Primary Identifier | MGI:6356323 | Allele Type | Targeted |
| Gene | Ptprz1 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Codon 1930 in exon 21 was altered from TGC to AGT. This resulted in a substition of cysteine with serine in the encoded protein (p.C1930S). A loxP site flanked neomycin selection cassette that was inserted into intron 21, was removed through Cre-mediated recombination. The mutation renders the protein tyrosine phosphatase catalytic domain inactive. |
