Primary Identifier | MGI:6356800 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Magi1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neo cassette replaced 3.2 kb of Mag1 genomic DNA, including most of exon 1 together with its ATG start codon as well as its upstream promoter region. This is a null allele of all three splice isoforms. Western blotting of the kidney cortex confirmed complete loss of Magi1 protein expression in the null mice. |