Primary Identifier | MGI:6356635 | Allele Type | Spontaneous |
Attribute String | Null/knockout | Gene | Zpld1 |
Inheritance Mode | Recessive | Strain of Origin | B6.129S4-Ccl2<tm1Rol>/J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A single C-to-T point mutation in exon 10 changing a CAG codon to TAG introducing a stop codon in place of a glutamine at amino acid 322 (p.Q322*), which is just after the furin cleavage site and eliminates the C-terminal region of the protein including the transmembrane domain. |