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Allele : Hspg2<tm2Soin> perlecan (heparan sulfate proteoglycan 2); targeted mutation 2, Raija Soininen

Primary Identifier  MGI:6358005 Allele Type  Targeted
Attribute String  Not Specified Gene  Hspg2
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  The region encoding the laminin-like globular domain3 (LG3), part of the antiangiogenic fragment called endorepellin, was deleted by replacing exons 91-96 by the neo cassette, leading to a perlecan protein lacking 156 amino acids at the C-terminus. The deletion does not change the reading frame and the last exon of the gene is intact.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories