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Allele : Was<tm2Lisw> Wiskott-Aldrich syndrome; targeted mutation 2, Lisa S Westerberg

Primary Identifier  MGI:6363560 Allele Type  Targeted
Attribute String  Constitutively active Gene  Was
Transmission  Germline Strain of Origin  129 x C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A T>C mutation was generated in exon 9 to change isoleucine codon 296 (ATT) to threonine (ACT) (p.Iso296Thr). This mutation corresponds to the p.I294T mutation found in human X-linked neutropenia patients.
  • mutations:
  • Single point mutation
  • synonyms:
  • WASp<I296T>,
  • WASp<I296T>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories