| Primary Identifier | MGI:6358101 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Kcnj8 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site together with an frt-flanked neomycin selection cassette was inserted in intron 1. Exon 2 contains the ATG translation initiation codon. A second loxP site was inserted distal to exon 2 in intron 2. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Subsequent Cre-mediated recombination in the germline resulted in the deletion of the loxP-flanked sequences including exon 2. |