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Allele : Gdpd1<em1Osb> glycerophosphodiester phosphodiesterase domain containing 1; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
Primary Identifier  MGI:6387028 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Gdpd1
Strain of Origin  (C57BL/6NJcl x DBA/2NJcl)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a 20 bp deletion (5-TCGTCCACCGCGGCTTTTTG-3) in the first exon. The sgRNA sequence used for microinjection was 5'-GAGAAGGCAAAAAGCCGCGG-3' for the first exon. The deletion causes a frameshift mutation leading to a premature termination codon after the 17th amino acid.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Gdpd1<-20>,
  • Gdpd1<-20>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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