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Allele : Bcl10<tm1.1Jrld> B cell leukemia/lymphoma 10; targeted mutation 1.1, Jurgen Ruland

Primary Identifier  MGI:6358379 Allele Type  Targeted
Attribute String  Conditional ready Gene  Bcl10
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The allele flanking exon 2 of Bcl10 with loxP sites was generated with the targeting construct containing a 0.7 kb short arm (SA) of Bcl10 intron 1, a frt-flanked neomycin resistance cassette followed by a 1.3 kb loxP flanked conditional arm comprising exon 2 and a 5 kb long arm, including exon 3 of the Bcl10 locus. Chimeric mice were mated for germline transmission of the targeted Bcl10 allele and crossed with ACT-FLPe mice to delete the neomycin resistance cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Bcl10<fl>,
  • Bcl10<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories