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Allele : Myh7<em1Dsr> myosin, heavy polypeptide 7, cardiac muscle, beta; endonuclease-mediated mutation 1, Deepak Srivastava

Primary Identifier	MGI:6360203	Allele Type	Endonuclease-mediated
Attribute String	Not Specified	Gene	Myh7
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 technology generated two point mutations, a G to A change, resulting in a leucine to phenylalanine substitution at amino acid 387 and a G to T change, resulting in a PAM site disruption.

mutations:
Nucleotide substitutions

synonyms:
Myh7<L387F>,
Myh7<L387F>

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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