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Allele : Adcyap1<tm1.1(cre/ERT2)Zjh> adenylate cyclase activating polypeptide 1; targeted mutation 1.1, Z Josh Huang
Primary Identifier  MGI:6360920 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Adcyap1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a CreER fusion gene followed by a frt-flanked neo cassette upstream of the stop codon of the adenylate cyclase activating polypeptide 1 (Adcyap1) gene. CreER incorporates cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain. The neomycin cassette was excised with Flp recombinase.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

1 Driven By

3 Publication categories





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