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Allele : Ykt6<em1(IMPC)J> YKT6 v-SNARE homolog (S. cerevisiae); endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6360693 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ykt6
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCACACTGTCCCCAACACAG and TGGATAGGAGAAGCAAGGCG, which resulted in a 248 bp deletion beginning at Chromosome 11 position 5,959,240 bp and ending after 5,959,487 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000105087 (exon 2) and 165 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 34 and early truncation 19 amino acids later.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ykt6<->,
  • Ykt6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories