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Allele : Sfpq<tm1.1Takea> splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); targeted mutation 1.1, Akihide Takeuchi

Primary Identifier	MGI:6360736	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Sfpq
Transmission	Germline	Strain of Origin	(C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP site and FRT flanked neo cassette were inserted in intron 1 and a loxP site was inserted in intron 4 via homologous recombination. Flp-mediated recombination removed the neo cassette.

mutations:
Insertion

cellLines:
Not Specified

earliestPublication:
Takeuchi A, et al. (2018) Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain. Cell Rep 23(5):1326-1341

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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