| Primary Identifier | MGI:6376207 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Wdr25 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TAGCAGACTGTCGAAGGCAG and CAAATGATCTGCATGCCCGT, which resulted in a 672 bp deletion beginning at Chromosome 12 position 108,980,296 bp and ending after 108,980,967 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000879483 (exon 4) and 524 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 265 and early truncation 15 amino acids later. |
