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Allele : Fsbp<em1(IMPC)J> fibrinogen silencer binding protein; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6376285 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Fsbp
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AATTAGCTCATTTTAAGCTG and TGTGGAATCGGCAGGATGGA, which resulted in a 914 bp deletion beginning at Chromosome 4 position 11,579,401 bp and ending after 11,580,314 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000243323 (exon 1) and 471 bp of flanking intronic sequence including the start site, splice acceptor and donor and is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories