| Primary Identifier | MGI:6384615 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Otc |
| Strain of Origin | NOD.Cg-Prkdc<scid> Il2rg<tm1Wjl>/SzJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/cas9 endonuclease-mediated genome editing was used to create an amino acid substitution at position 129 altering arginine to histidine (R129H; CG to CA) in exon 4. This mutation was identified as a human early-onset ornithine transcarbamylase deficiency associated variant allele. |