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Allele : Cped1<em1(IMPC)J> cadherin-like and PC-esterase domain containing 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6379302 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cped1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TAAATCATCACACTCTTTAC and TTGGAACCACTGTATCTGTG, which resulted in a 260 bp deletion beginning at Chromosome 6 position 22,051,254 bp and ending after 22,051,513 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001312394 (exon 3) and 153 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 145 and early truncation 17 amino acids later. There is a 2 bp TT insertion at the deletion site.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories