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Allele : Klhl34<em1(IMPC)J> kelch-like 34; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6367818 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Klhl34
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCTGGAGGCATCCCATAACA and TAAGGAGGTGAACAAGGCCT, which resulted in a 1657 bp deletion beginning at Chromosome X position 157,818,351 bp and ending after 157,820,007 bp (GRCm38/mm10). This mutation deletes 1572 bp of ENSMUSE00000543784 (exon 1) and 83 bp upstream of the ATG start and is predicted to generate a null allele. There is a 6 bp insertion TCCAGC at the deletion site.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories