| Primary Identifier | MGI:6388590 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Efcab3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATAGGATGCTAAGCTCTCCA and AAAACATCCAGAAGCTTTGG, which resulted in a 269 bp deletion beginning at Chromosome 11 position 104,693,210 bp and ending after 104,693,478 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000353657 (exon 4) and 154 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 63 and early truncation 5 amino acids later. |
