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Allele : Kit<em1(cre)Bzsh> KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 1, Bin Zhou

Primary Identifier	MGI:6361908	Allele Type	Endonuclease-mediated
Attribute String	Recombinase	Gene	Kit
Strain of Origin	C57BL/6J	Is Recombinase	true
Is Wild Type	false

molecularNote

The mouse line was generated by homologous recombination using the CRISPR/Cas9 technology. A self-cleaving 2A peptide and complementary DNA encoding Cre recombinase replaced the translational stop codon and inserted in Kit gene.

mutations:
Insertion

synonyms:
Kit-2A-Cre,
Kit-2A-Cre

earliestPublication:
He L, et al. (2019) Reassessment of c-Kit(+) Cells for Cardiomyocyte Contribution in Adult Heart. Circulation 140(2):164-166

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

2 Publication categories

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