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Allele : Aars2<tm1.1Htyy> alanyl-tRNA synthetase 2, mitochondrial; targeted mutation 1.1, Henna Tyynismaa

Primary Identifier  MGI:6368036 Allele Type  Targeted
Gene  Aars2 Transmission  Germline
Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  TG to GC nucleotide changes at position 2230-2231, resulting in a cysteine to alanine change at amino acid 744, were introduced in exon 16. A neomycin resistance gene flanked by FRT sites was also introduced into intron 17. Flp-mediated recombination in the ES cells removed the selection cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • C744A,
  • C744A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele