Primary Identifier | MGI:6368036 | Allele Type | Targeted |
Gene | Aars2 | Transmission | Germline |
Strain of Origin | (129S6/SvEvTac x C57BL/6NCrl)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | TG to GC nucleotide changes at position 2230-2231, resulting in a cysteine to alanine change at amino acid 744, were introduced in exon 16. A neomycin resistance gene flanked by FRT sites was also introduced into intron 17. Flp-mediated recombination in the ES cells removed the selection cassette. |