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Allele : Ttc21a<em1Fzh> tetratricopeptide repeat domain 21A; endonuclease-mediated mutation 1, Feng Zhang

Primary Identifier  MGI:6368822 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ttc21a
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a frameshift mutation (c.2534del) which is predicted to cause premature translational termination. RT-qPCR assays revealed that testicular mRNA expression is reduced to approximately 26% of that in wild-type controls.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ttc21a<mut>,
  • Ttc21a<mut>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele