| Primary Identifier | MGI:6385872 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Ces2c |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATTACAGAAAACTAACCCAG and GGAATAACATGGATATACTA, which resulted in a 469 bp deletion beginning at Chromosome 8 position 104,847,963 bp and ending after 104,848,431 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001220643 (exon 2) and 258 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 26 and early truncation 7 amino acids later. |
