| Primary Identifier | MGI:6385899 | Allele Type | Targeted |
| Gene | Trf | Transmission | Germline |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Two A to T nucleotide substitutions were introduced resulting in a tyrosine to phenylalanine change at amino acid 448 (Y448F) and at amino acid 537 (Y537F). A FRT-flanked neomycin resistance cassette was inserted upstream of the two mutations. These two mutations abrogate iron binding in the C lobe of transferrin. |
