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Allele : Rrh<tm1Ght> retinal pigment epithelium derived rhodopsin homolog; targeted mutation 1, Gabriel H Travis

Primary Identifier  MGI:6368179 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Rrh
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Using homologous recombination in ES cells, a targeting vectir replaced a 4.3-kb fragment starting at the initiator methionine in exon 1 and a part of intron 1 of a mouse Rrh genomic fragment with a LacZ-coding region followed by a neomycin resistance cassette (PGK-Neo). Immunoblot analysis on retinal pigment epithelium (RPE) homogenates and immunohistochemistry of eyecup sections confirmed absence of protein in homozygous mice. It is a null allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Rrh<->,
  • Rrh<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele