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Allele : Tbx6<em1Fzh> T-box 6; endonuclease-mediated mutation 1, Feng Zhang

Primary Identifier  MGI:6368858 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tbx6
Strain of Origin  FVB/NJ Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a 1 bp insertion in exon 2 resulting in a frame shift mutation that leads to premature translational termination damaging the key T-box domain.
  • mutations:
  • Insertion
  • synonyms:
  • Tbx6<->,
  • Tbx6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories