Primary Identifier | MGI:6368858 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Tbx6 |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a 1 bp insertion in exon 2 resulting in a frame shift mutation that leads to premature translational termination damaging the key T-box domain. |