Primary Identifier | MGI:6389578 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Frem2 |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRIPSR/Cas9 technology generated an A to T mutation at position 6466 resulting in an arginine to tryptophan change at amino acid 2156 (R2156W). This mutation corresponds to the R2167W (c.6499C>T) mutation seen in a cryptophthalmos patient. |