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Allele : Frem2<em2Hali> Fras1 related extracellular matrix protein 2; endonuclease-mediated mutation 2, Haotian Lin

Primary Identifier  MGI:6389578 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Frem2
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRIPSR/Cas9 technology generated an A to T mutation at position 6466 resulting in an arginine to tryptophan change at amino acid 2156 (R2156W). This mutation corresponds to the R2167W (c.6499C>T) mutation seen in a cryptophthalmos patient.
  • mutations:
  • Single point mutation
  • synonyms:
  • Frem2<R2156W>,
  • Frem2<R2156W>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele