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Allele : Fahd1<em1(IMPC)J> fumarylacetoacetate hydrolase domain containing 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6401314 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Fahd1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCAGGCTTGTCAGTTCCCTA and TTGGCTGTGAACTCTATGGG, which resulted in a 1932 bp deletion beginning at Chromosome 17 position 24,848,493 bp and ending after 24,850,424 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000343391 (exon 1) and 459 bp of flanking intronic sequence including the splice acceptor, donor and start site. It is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories