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Allele : Mef2b<tm2Rdf> myocyte enhancer factor 2B; targeted mutation 2, Riccardo Dalla-Favera

Primary Identifier  MGI:6400973 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Null/knockout Gene  Mef2b
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene and STOP cassette pair was inserted into intron 2. Exon 3 was replaced with a version containing a mutation that changes aspartic acid codon 83 into a valine codon (p.D83V). This creates a conditional-ready null allele that expresses the full mutated transcript only after cre-mediated removal of the neo and STOP cassettes.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Mef2b<stopD83V>,
  • Mef2b<stopD83V>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories