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Allele : Arel1<em1Bbc> apoptosis resistant E3 ubiquitin protein ligase 1; endonuclease-mediated mutation 1, Bill B Chen

Primary Identifier  MGI:6392853 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Arel1
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 13 was targeted using an sgRNA and CRISPR/Cas9 technology, resulting in a 91 bp deletion spanning the 3' end of exon 13 and the 5' end of intron 13. The transcripts expressed from this allele skip the 3'-incomplete exon 13 (resulting in a frameshift and premature termination) and total transcription levels are reduced.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Kiaa0317<->,
  • Kiaa0317<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories