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Allele : Klhl3<tm1.1Slin> kelch-like 3; targeted mutation 1.1, Shih-Hua Lin

Primary Identifier  MGI:6393409 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Klhl3
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An A to G change resulting in a methionine to valine substitution at amino acid 131 (M131V) was introduced in exon 5 and a loxP flanked neomycin selection cassette was inserted upstream of exon 5. Cre-mediated recombination removed the neomycin cassette. This corresponds to the M78V mutation in individuals with pseudohypoaldosteronism.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Klhl3<M131V>,
  • Klhl3<M131V>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories