| Help | About | Contact Us

Allele : Ins2<tm1.1(cre)Wpiz> insulin II; targeted mutation 1.1, Weiping Zhang

Primary Identifier	MGI:6423077	Allele Type	Targeted
Attribute String	Recombinase	Gene	Ins2
Transmission	Germline	Strain of Origin	129/Sv
Is Recombinase	true	Is Wild Type	false

molecularNote

An IRES-Cre-bpA DNA sequence and an frt-flanked neomycin selection cassette was inserted between the stop codon ad the 3'UTR in the third exon. The neomycin selection cassette was subsequently removed via FLP-mediated recombination in the germline.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Ins2-cre,
Ins2-cre

earliestPublication:
Li L, et al. (2016) Knockin of Cre Gene at Ins2 Locus Reveals No Cre Activity in Mouse Hypothalamic Neurons. Sci Rep 6:20438

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

6 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76676818

MouseMine