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Allele : Atp6v0b<em1(IMPC)J> ATPase, H+ transporting, lysosomal V0 subunit B; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6402781 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Atp6v0b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGTTTGGGTCTAGTGCACAG and GAGTAAACTGGGAGTCCGGT, which resulted in a 3425 bp deletion beginning at Chromosome 4 position 117,884,089 bp and ending after 117,887,513 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000761417-ENSMUSE00000737163 (exons 1-8) and 2425 bp of flanking intronic sequence including the splice acceptor, donor and start site and is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories