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Allele : Ndnf<tm2.1(flpo)Ispgl> neuron-derived neurotrophic factor; targeted mutation 2.1, Ivo Spiegel

Primary Identifier  MGI:6393604 Allele Type  Targeted
Attribute String  Recombinase Gene  Ndnf
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  true Is Wild Type  false
molecularNote  The targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a FlpO recombinase sequence into the 3' UTR in exon 4 of the neuron-derived neurotrophic factor (Ndnf) gene. The construct also included a frt-flanked neomycin resistance cassette. After homologous redcombination in ES cells, the resulting chimeric mice were bred with flp recombinase expressing mice to remove the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Ndnf-IRES-FlpO,
  • Ndnf-IRES-FlpO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

7 Publication categories