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Allele : Prob1<em1(IMPC)J> proline rich basic protein 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6402744 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Prob1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTTTTAAAAAGGTGGCAGC and TTTAAGACGCTTTGACCCCG, which resulted in a 4975 bp deletion beginning at Chromosome 18 position 35,650,319 bp and ending after 35,655,293 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001322141 (exon 1) and 87 bp of flanking intronic sequence including the splice acceptor, donor and start site and is predicted to generate a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories