| Primary Identifier | MGI:7563973 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Umod |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G to A change at position 512 (c.G512A) resulting in a cysteine to tyrosine substitution at amino acid 171 (p.C171Y) was introduced in the cysteine-rich domain. An FRT-flanked neomycin resistance cassette was also inserted and was removed via flp-mediated recombination. This corresponds to the C170Y mutation identified in individuals with late-onset autosomal dominant tubulointerstitial kidney disease. |
