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Allele : Zbed6<em1(IMPC)J> zinc finger, BED type containing 6; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6393538 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Zbed6
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTCAGATTGCCAACTACACA and TCTTCTGCCAGGAGAGATTG, which resulted in a 2700 bp deletion beginning at Chromosome 1 position 133,656,861 bp and ending after 133,659,560 bp (GRCm38/mm10). This mutation deletes 2700 bp from ENSMUSE00001073319 (exon 1) and is predicted to cause a change of amino acid sequence after residue 12, deletion of 901 amino acids and a return to frame for the last 67 amino acids and expected termination.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories